Monthly Archives: March 2019


National Endometriosis Awareness Month of March 2019

Endometriosis AwarenessInfertility is a classic and devastating symptom of endometriosis. National Endometriosis Awareness Month in 2019 is a movement to increase knowledge about this leading cause of female infertility. Every March, a movement for awareness about endometriosis takes place worldwide. The aim of the movement is to increase awareness and highlight the symptoms of this debilitating condition that affects the fertility of an estimated 176 million women worldwide – 1 in 10 women. Endometriosis has a devastating effect on the quality of life of sufferers due to painful symptoms and infertility.

National Endometriosis Awareness Month

  • 60 percent of women suffering from endometriosis have no symptoms other than the inability to conceive naturally.
  • An estimated 6.5 million women in the U.S. – and 200 million globally – are affected by endometriosis
  • The most common symptom of endometriosis is painful periods
  • Endometriosis often goes undiagnosed or is misdiagnosed for years because women and teenage girls believe painful periods are normal – this myth must be denounced

Avid Promoter of Endometriosis Awareness

The fertility specialists at New Hope Fertility Center are avid promoters of Endometriosis Awareness, with the specific goals of:

  • Promoting a greater awareness and understanding of endometriosis as a real and debilitating disease
  • Highlighting the consequences of living with endometriosis for the women suffering from it
  • Creating a greater awareness and understanding of endometriosis among the medical profession, employment sector, and society in general
  • Seeking a best practice and consistent care and treatment for women suffering from endometriosis
  • Providing an opportunity for those whose live have been affected by endometriosis to play a key role in helping make a difference

Endometriosis Awareness

Endometriosis affects a woman’s reproductive and surrounding organs when uterine lining tissue (endometrium) grows outside of the uterus and into other areas of her body.

  • Abdominal cavity and pelvis
  • Ovaries
  • Fallopian tubes and supporting ligaments

This errant tissue is generated by hormones creating endometrial cells. The disease causes adhesions (scar tissue), lesions, and blood-filled cysts. Endometrial cells appearing in abnormal locations cause endometriosis. When these errant endometrial cells grow and then sluff off, there is no escape outlet from the body, and internal bleeding leads to:

  • Inflammation
  • Pelvic pain
  • Formation of scar tissue (adhesions)

Symptoms of Endometriosis

Infertility is a classic and devastating symptom of endometriosis. Other pelvic pain symptoms:

  • Pain in the lower abdomen and/or lower back that can radiate to the legs
  • Pain before and during periods
  • Mid-cycle pain as a woman’s monthly egg ruptures through the ovary (ovulation pain – Mittelschmerz)
  • Lengthy and heavily bleeding periods, with or without clots
  • Irregular periods with spotting before period begins
  • Fatigue and/or depression

Infertility Caused by Endometriosis

Women with endometriosis are three to four times less likely to conceive or maintain a pregnancy. Endometriosis causes infertility in several different ways.

  • Anatomical pelvic/tubal adhesions – tubal infertility
  • Diminished ovarian reserve – reduced egg supply
  • Toxic pelvic peritoneal factors – toxic pelvic environment
  • Autoimmune implantation dysfunction – embryo implantation failure

Diagnosing and Treating Endometriosis

The suspicion of endometriosis usually begins based on a woman’s symptoms and is followed up with blood and ultrasound testing to detect ovarian cysts. Laparoscopy is the definitive method of accurately diagnosis endometriosis and determining its severity.

  • Endometriosis is usually treated by prescribing anti-hormonal drugs with the purpose of blocking estrogen production and shrinking lesions
  • When medications fail, lesions are can be removed through laparoscopic surgery

More Helpful Pregnancy Resources

It is important to work with a fertility doctor having the expertise required to design a customized fertility treatment protocol meeting your personal needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 917.525.5496.

Dr. Zhang Explains How Needle-Free IVF Works

42109089 - asian couple and babyOur innovative Needle-Free IVF protocol does not require injections or blood draws. Look: The patient’s ovaries are stimulated into producing multiple egg follicles through the use of oral fertility medications. That’s not all. Hormone levels are measured through urine and saliva tests. This holistic IVF protocol eliminates the fear, pain, and anxiety many patients experience with injections and blood draws. Needle-Free IVF also lowers the patient’s cost of fertility medications.

Needle-Free IVF is New – Simple – Pain Free – Convenient

  • No shots
  • No needles
  • No blood draws

Needle-Free IVF Benefits

Through Needle-Free IVF, patients are treated in a less-invasive manner.

  • No shots
  • No needles
  • No injections
  • No blood draws

Needle-Free IVF Protocol

How is Needle-Free IVF patient-friendly?

  • Improves patient safety
  • Improves patient compliance with medication regimen
  • Reduces possibility of error in medication administration
  • Eliminates the risk of accidental needle sticks

Needle-Free IVF Fertility Medications

Depending on the woman’s medical needs, an oral fertility medication – typically Clomid and/or Letrozole– are prescribed to gently stimulate her ovaries into producing multiple eggs. Synarel is administered nasally for 3 days at the beginning of the cycle and then again 36 hours prior to surgical egg retrieval to trigger ovulation.

  • Clomid and/or Femara to stimulate egg production
  • Synarel to trigger ovulation
  • Oral progesterone tablets
  • Vaginal progesterone suppositories

Compared to the Mini-IVF Protocol

In Very Well Family (8/20/18) – Dr. John Zhang explains that producing too many eggs with large doses of injectable fertility drugs can backfire and cause medical problems, such as PCOS. Look: Our Mini-IVF protocol is a simple, convenient, and patient-friendly fertility treatment protocol calling for a minimal amount of stimulating fertility medication injections to produce 3 to eggs. Bottom Line: A woman’s body no longer needs to be forced into producing multiple eggs to achieve a successful IVF pregnancy.

Compared to Conventional IVF Protocol

A Conventional IVF protocol calls for daily injections of hormone medications to produce multiple egg follicles – 10 – 15 one cycle. These egg are retrieved surgically and then fertilized in vitro for transfer to the woman’s uterus. Excess quality embryos may be cryopreserved for future Frozen Embryo Transfer (FET) procedures.

strong>One Good Egg Policy

Customized IVF care is the best. Remember: It only takes one good egg and one healthy sperm to make a baby. Our focus is to help you produce good quality eggs during a fresh IVF cycle – not a high quantity of eggs using large doses of injectable fertility medications.  This policy is perfectly suited for our new Needle-Free IVF protocol.

Difficult Patients Welcome

Women diagnosed as difficult or hopelessly infertile by other fertility clinics are welcomed at New Hope Fertility Center. The best part? Because of our One Good Egg Policy, we happily accept candidates for IVF that other fertility clinics decline to treat and have proven success where others failed to even try.

Egg Collection Results and Success Rates

Our Needle-Free IVF protocol has resulted in comparable egg collection results as that of the Conventional IVF protocol. We are – on average – able to retrieve at least 10 eggs from patients who have undergone our Needle-Free IVF protocol. These results are reassuringly comparable with other IVF protocols in terms of number of eggs collected and pregnancy success rates.

High Tech IVF Laboratory

Our goal is to maximize every patient’s chances of having a successful pregnancy. At New Hope Fertility Center, we offer the latest:

  • IVF technology
  • IVF ingenuity
  • IVF customization

Our IVF laboratory is comprised of a powerful air filtration system to facilitate the best conditions for success of procedures and research. We have one of the largest and most powerful air filtration systems in the world. Bottom Line: This quality air filtration system provides optimal clean air pressure in every laboratory process.

Celebrated Needle-Free IVF Expertise

It is important to work with a fertility doctor having the expertise required to design a customized IVF treatment protocol meeting your personal needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 917.525.5496.

How Quality Sleep Will Increase Your Natural Fertility Level

10899214 - beautiful girl sleeps in the bedroomThe National Sleep Foundation has found through studies that sleep has a powerful influence on a woman’s reproductive hormonal system.

Sleep deprivation adversely affects your BMI, your mood, and your stress level. Your Follicle Stimulating Hormone (FSH) level is directly affected by lack of sleep. Your FSH level should ideally be at its highest level just before you ovulate.

Let’s take a look into:

  • Sleep and BMI
  • Sleep and Mood
  • Sleep and Stress

Women averaging 7 to 9 hours of sleep each night had a 20 percent higher FSH level than those who go 6 or fewer hours – regardless of age, BMI, mood, or stress level.

Bottom Line:

Enhancing your quantity and quality of sleep will increase your natural fertility level.

  • Improve your BMI
  • Improve your Mood
  • Decrease your and stress level

Quality Sleep Will Increase Your Natural Fertility Level

To increase your natural fertility level, you must establish a healthy sleep pattern and get your circadian rhythm – and hormonal levels – in sync. Look: When a woman’s body is deprived of rest, she can experience weight gain, mood disorders, and increased stress levels. Why is this important? Adequate sleep will improve your natural fertility level. Women in their prime childbearing years (25 to 35) need 7 to 9 hours of quality sleep every night during a work week to sustain an optimum fertility level.

Sleep and BMI

A healthy adult Body Mass Index (BMI) is between 18.5 and 24.9. Look: A 2016 review of studies shows that not getting enough sleep leads women to consume an average of 385 more calories the next day.

Here’s the real story about women who don’t get enough sleep.

  • They gain weight
  • The make less healthy food choices
  • They eat foods higher in fat
  • They eat low protein foods

Over a five year period, women can gain 2.1 BMI points for every hour of sleep they lose. Why is this important? A two pound weight gain can easily throw a woman off of her healthy BMI.

The takeaway. Sleep is an important moderator of neuroendocrine function and glucose metabolism. Sleep loss alters metabolic and endocrine alterations.

Sleep and Mood

Your quantity and quality of nightly sleep is directly connected with your mood when you wake. It can’t be emphasized enough, chronic insomnia increases the risk of developing a mood disorder – especially depression and/or anxiety.

Sleep-related mood disorders can be self-corrected through a variety of methods.

  • Improved sleep habits
  • Behavioral interventions
  • Sleep assessments
  • Mood disorder assessments

Look: Every woman realizes that she is more vulnerable to certain emotions after a sleepless night.

  • More irritable
  • Short-tempered
  • Stressed out

It’s pretty common to realize that once you’ve had a good night’s sleep, your mood becomes stabilized throughout the next day.

A Harvard Sleep Study confirms that sleep deprivation has a significant adverse effect on one’s mood. University of Pennsylvania researchers found that limiting sleep to 4.5 hours per night for one week causes:

  • Stress
  • Anger
  • Sadness
  • Mental exhaustion

That’s not all. Making it even more difficult to sleep, disruptions in mood increase:

  • Anxiety
  • Agitation
  • Arousal

These affects make it difficult to get to sleep and rest comfortably because you are awake and alert. These abnormally exaggerated responses to stress make one suffer from sleep deprivation.

Sleep and Stress

Stress keeps us alert and energetic. Although stress is an innate force helping us to perform at top level in our daily activities, too much tension and anxiety can cause a person to experience sleep deprivation. Stress is a natural response to daily life.

Here’s the catch. Too much stress causes:

  • Sleep deprivation
  • Depression
  • Tension
  • Anxiety
  • Lack of concentration
  • Apathy
  • Inadvertent mistakes

You must manage your stress to enhance your reproductive health and overall well-being. The amount of stress a woman experiences while undergoing In Vitro Fertilization (IVF) treatment can be determinative of pregnancy success or failure.

That’s not all. Research has shown that stress can reduce your chances of conceiving through IVF. Stress has been linked to an egg’s ability to be fertilized and an embryo’s ability to implant in a woman’s uterine lining. Studies have shown that women undergoing IVF with anxiety had fewer eggs retrieved and fewer embryos implanting successfully.

Bottom Line: Lessening stress levels will help to increase your chances of a successful IVF cycle.

Improving Fertility with Quality Sleep

The fertility specialists at New Hope Fertility NYC recommend some simple approaches to achieve quality sleep. These measures will help with relaxation at the desired time sleep is needed.

The take away:

  • Maintain a comfortable sleep environment
  • Encourage a balance of nutrition and exercise

Implement a strict sleep schedule and stick to it. The human body flourishes on routine. Having a regular schedule of when you fall asleep and awake will help your body regulate its internal clock. Designate a time you normally feel tired. Making a scheduled bed time will keep you from spending a lot of time struggling to fall asleep. Keep your sleep schedule consistent on the weekends and holidays.

  • Maintain a regular sleep-wake schedule
  • Avoid caffeine, alcohol, nicotine – these interfere with sleep
  • Make your sleeping space comfortable
  • Establish a calming pre-sleep routine – avoid stimulating news or entertainment
  • Go to sleep when you are tired – don’t watch the clock and procrastinate rest
  • Limit your light exposure in the evening – turn off the TV
  • Limit eating and drinking before retiring to bed – let your stomach rest
  • Exercise regularly – 30 minutes per day – but not before bedtime

More Helpful Resources to Increase Your Natural Fertility Level

It is important to work with a fertility doctor having the experience to accurately diagnose the root cause of your infertility. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center in NYC – call 917.525.5496.

How Embryo Quality is Enhanced by EmbryoScope Technology

Two scientists working together in lab looking at dataDr. John Zhang is proud to be one of very few fertility specialists in the world to use EmbryoScope technology. Quality embryo development is crucial to a successful IVF pregnancy. Here’s the deal: Embryologists must observe embryos culturing in vitro regularly in order to make accurate assessments of their development progress and quality. Minimizing the disturbance of embryos has been aided by time-lapsed technology – the EmbryoScope. Why does this matter? Before time-lapse technology, embryos used to be physically removed from the incubator by the embryologist for observation. This physical movement would disturb the culturing process by exposing the embryo to stress and fluctuations.

EmbryoScope Time-Lapse Technology

The EmbryoScope is an innovative, cutting-edge, time-lapsed photography and software solution. Bottom Line: The EmbryoScope allows the growth and development of embryos in vitro to be monitored without disturbing the culturing process.

The EmbryoScope improves IVF outcomes.

  • Quantitative data on an embryo’s early stage of development in vitro
  • Objective information on an embryo’s early stage of development in vitro
  • Utilizes time-lapsed photography and software
  • No need to manipulate embryos within the incubator in vitro
  • No need to remove the embryos from the incubator in vitro

Candidates for EmbryoScope technology:

  • Couples having previous failed IVF attempts
  • Couples suffering from recurrent pregnancy loss (miscarriage)

Embryology Expertise

From a cell – to a newborn baby – embryology is the branch of biology and medicine focused on the study of an embryo from the point of fertilization through development to the fetus stage. The practice of embryology is key to pregnancy success through IVF technology.

Working with fertility doctors to successfully treat every patient’s underlying cause of infertility, the clinical embryologists at New Hope Fertility Center are responsible for:

  • Assisting in the surgical retrieving of a woman’s eggs
  • Performing post-surgical retrieval tests on eggs
  • Performing in vitro tests on embryos
  • Maintaining patient clinical records

Our acclaimed team of embryologists give careful attention to nurturing quality embryos as they develop in vitro. Only quality embryos are transferred to the patient’s uterus.

  • Quality embryos have the highest chance of implantation into a woman’s uterine lining
  • Quality embryos thrive into a fetus
  • Quality embryos have the best chance of achieving a full-term, healthy pregnancy

After Egg Retrieval and In Vitro Culturing

Excess, quality embryos produced during a fresh IVF cycle are cryopreserved for future transfers via Frozen Embryo Transfer (FET). Only the highest quality embryos are cryopreserved for the best chances of a future FET pregnancy success.

Embryology Roles in the IVF Process

Our cutting edge laboratory technology provides embryos culturing in vitro with an optimum environment for healthy development prior to fresh transfer and/or cryopreservation for future FETs.

  • HRSS – High Resolution Sperm Selection is technology used to identify and choose only highest quality sperm cells for fertilization of a healthy egg
  • ICSI – Intracytoplasmic Sperm Injection is technology used to treat male factor infertility by assisting in each healthy egg’s direct fertilization with only a high quality sperm
  • Assisted Hatching is technology used to help embryos erupt from their shell and become more amendable to implantation in the uterine lining
  • IVF/M – In Vitro Maturation is technology used to surgically retrieve a woman’s immature eggs and mature same in vitro before fertilization via ICSI
  • EmbryoScope technology is used to gather time-lapsed data by monitoring every embryo’s development without disruption of the in vitro culturing process

HRSS – High Resolution Sperm Selection

Embryologists at New Hope Fertility Center choose only the healthiest sperm to fertilize an egg in vitro. HRSS technology provides embryologists with the ability to view sperm at 6000 x magnification using Differential Interference Contrast (DIC) microscopy. Through HRSS, an embryologist can view the physical details of each sperm – its shape, size, and motility – looking for good morphological appearance. Healthy sperm is essential to the development of a quality embryo in vitro. Normal chromosomes and less fragmentation in DNA are key factors that play a significant role in the quality of an embryo.

ICSI – Intracytoplasmic Sperm Injection

ICSI is an IVF laboratory ancillary procedure designed to help resolve male-factor infertility due to low sperm count or poor sperm quality. ICSI is the micromanipulation of fertilizing an egg by injecting a single sperm directly into the cytoplasm of a mature egg using a pipette (glass needle).

Assisted Hatching

A computer-assisted laser procedure – known as Assisted Hatching – helps the mass of cells inside an embryo escape during transfer for better uterine lining implantation success. A tiny opening is made in the Zona Pellucida through a computer-assisted laser after the embryo has cultured for up to five days.

(IVF/M) In Vitro Maturation

Through IVF/M – in vitro fertilization with maturation – immature eggs are retrieved for maturation in vitro and fertilization using ICSI.

EmbryoScope Technology Expertise

To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 917.525.5496.

Dr. Zhang Explains IVF and FET Pregnancy Success Rates

17365267 - happy african family isolated on whiteCorrectly interpreting the data reporting yearly pregnancy success by nationwide fertility clinics is critical for IVF patients. Here’s the deal: This data helps patients choose the best fertility clinic giving them the highest chances of pregnancy success through IVF technology. It can’t be emphasized enough. Before choosing a fertility clinic, you must know how to read and interpret official IVF pregnancy success records. Why is this important? A substantial amount of IVF pregnancy success is accomplished through Frozen Embryo Transfer (FET) procedures.

  • You should inquire about embryology policies and procedures
  • You should inquire about FET pregnancy success rates
  • You should inquire about recent accomplishments in IVF/FET research, as well as changes in IVF/FET technology

IVF and FET Pregnancy Success

IVF and FET pregnancy success is reliant on many patient-focused variables.

  • Age
  • Infertility diagnosis
  • History of previous pregnancies
  • History of previous miscarriages
  • Number of failed IVF cycles – fresh and frozen embryo transfers
  • Number of embryos transferred in a single cycle
  • IVF protocol recommended
  • IVF ancillary procedures used – ICSI, Assisted Hatching, In Vitro Maturation
  • Genetic testing to select only quality embryos for transfer – PGD, PGS/NGS
  • Gender Selection

IVF Protocols

Difficult Patients Welcome

We don’t refuse those patients diagnosed as a difficult case. At New Hope Fertility Center, we welcome patients rejected by other fertility specialists because they are deemed to be hopelessly infertile.

  • No refusals based on a woman’s advanced maternal age
  • No refusals based on low FSH levels
  • No refusals based on the number of potential eggs (follicles) a woman can produce per fresh cycle
  • No refusals because a woman does not respond well to fertility medication

One Good Egg Policy

Customized IVF care is the best. Remember: It only takes one good egg and one healthy sperm to make a baby. Our focus is to help you produce good quality eggs during a fresh IVF cycle – not a high quantity of eggs using large doses of injectable fertility medications.

SART and CDC

The Society for Assisted Reproductive Technology (SART) is the official source to which fertility specialists report their IVF and FET pregnancy success rates. You can also look to the Center for Disease Control (CDC) for IVF and FET pregnancy success and birth rates.

SART is a fertility specialist organization that is dedicated to setting professional standards in the practice of Assisted Reproductive Technology (ART). Its mission is to inform and serve fertility specialists and their patients.

From the SART website:

Accurate and complete reporting of IVF pregnancy success rates reported by the members of SART is complicated because of the variation of ART practice from clinic to clinic. These differences may inflate or lower IVF pregnancy rates provided by another clinic.

IVF and FET pregnancy success rates vary from clinic to clinic based on:

  • Differences in patient selection
  • Differences in treatment approaches
  • Differences in IVF cycle reporting practices

All fertility specialists in the United States report and verify data on their IVF and FET pregnancy procedures over a calendar year period.

Valuing IVF and FET Pregnancy Success Rates

Yearly data on IVF and FET pregnancy success rates is a valuable source of information for every patient. This rich data gives patients a better idea of their average chances of pregnancy through IVF and FET.

IVF and FET pregnancy success rates can be misleading when based on a small number of transfer procedure performed. At New Hope Fertility Center, we omit graphed data when there are less than 20 transfers in a segment.

Reading SART IVF and FET

  • Start by clicking here
  • Check the box agreeing to SART’s terms and conditions of use
  • Click on the 2015 Preliminary box to the right: I agree to the limitations on use of the data in this report and agree to abide by the SART Website Terms and Conditions of Use
  • Scroll down to view our Profile, Services, and IVF Pregnancy Success Rates

Customized IVF and FET Expertise

It is important to work with a fertility doctor having the expertise required to design a customized IVF and FET treatment protocol meeting your personal needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 917.525.5496.