Category Archives: ICSI and IVF


How ICSI Technology Enhances IVF Egg Fertilization

11255204 - human sperm and egg lifeICSI – Intracytoplasmic Sperm Injection – is a specialized egg fertilization technique used during the IVF process. Look: ICSI bypasses a number of common reproductive conditions preventing sperm from fertilizing an egg. A single sperm cell is injected directly into an egg under the guidance of a microscope. ICSI has revolutionized the treatment of male-factor infertility.

Why is ICSI important?

  • ICSI is used to maximize the rate of egg fertilization
  • ICSI lessens the chances of sperm not being able to penetrate the wall of the egg

ICSI is recommended for most couples undergoing IVF – especially these candidates:

  • Unexplained infertility – known as idiopathic infertility – when the cause cannot be pinpointed
  • Male-factor infertility – a man’s sperm is not able to fertilize a woman’s egg
  • Combined female- and male-factor infertility

Today, ICSI is routinely recommended to improve fertilization in all IVF cases – regardless of diagnosis.

Sperm Retrieval for ICSI

When a man has a low sperm count and/or motility, a semen sample is collected through masturbation. The semen sample is processed in a special solution to obtain optimum ICSI results.

When a man is suffering from azoospermia – no sperm in ejaculate – sperm is microsurgically retrieved from the testicle or epididymis. This is commonly known as testicular sperm retrieval. Microsurgery to remove sperm from the testicles or epididymis can be performed under local or general anesthesia and requires short recovery periods.

Obstructive Azoospermia (no sperm in semen) can be corrected by the surgical removal of sperm directly from the testis or epididymis of the testicle.

  • Microsurgical Epididymal Sperm Aspiration (MESA)
  • Percutaneous Epididymal Sperm Aspiration (PESE)
  • Testicular Sperm Extraction (TESA)

Non-Obstructive Azoospermia (sperm count with impaired sperm) may be caused by hormonal problems, testicular failure, varicocele, or varicose veins in the testicles. Non-Obstructive Azoospermia can be corrected through TESE – testicular sperm extraction. TESE is a surgical technique using fine needle aspiration performed with local anesthesia.Read more: How ICSI Technology Enhances IVF Egg Fertilization