How NGS Works to Increase IVF Pregnancy Success Rates

MicroscopeNew advancements in the fields of embryology and genetics testing have significantly improved In Vitro Fertilization (IVF) pregnancy success rates. The latest technological innovation, Next Generation Sequencing (NGS) enhances how embryologists analyze and select quality embryos for transfer. The embryologists at New Hope Fertility Center give steadfast attention nurturing embryos as they develop in vitro.

Benefits of Next Generation Sequencing (NGS)

Quality embryos identified in vitro through NGS have the highest chance of implantation. Using NGS in conjunction with IVF, high quality embryos are transferred to the patient’s uterus for the best chance of a healthy, successful pregnancy.

Through NGS technology, you can identify the gender of your embryos in conjunction with your IVF procedure. Gender identification and selection is a natural byproduct of NGS technology.

NGS identifies the most suitable and healthiest embryo to transfer by detecting chromosomal deficiencies – aneuploidy – an extra or missing chromosome. NGS is set to replace Preimplantation Genetic Screening (PGS). NGS allows embryologists to view the genetic makeup of an embryo at levels far exceeding PGS technology.

  • Significant improvement in pregnancy outcomes
  • Enhancement of the knowledge embryologists employ while selecting embryos
  • Substantially more accurate and faster than PGS
  • Comprehensive results
  • Higher resolution
  • Detects more translocations
  • Reduced errors
  • Less costly than PGS

How NGS Works

NGS may be conducted as a standalone test – or in conjunction with PGS – at a quicker completion rate. NGS also detects mosaicism – when an embryo’s cells exhibit a different chromosomal content.

As a woman advances in age, the chance for chromosomal abnormalities in embryos increases. Low quality embryos result in:

  • Low pregnancy success rates
  • High miscarriage rates
  • High chance for birth defects

30% Increase in IVF Pregnancy Success Rates

Universal blastocyst-stage NGS is recommended because the procedure can help increase the chances of a successful pregnancy by 30 percent.

State-of-the-art embryo biopsy techniques and genetics technologies have proven to increase IVF pregnancy rates. Through the medical marvel of NGS in conjunction with IVF, genetic and chromosomal abnormalities can be detected in embryos.

After the gender of your embryos are identified through NGS, you can now choose the gender of the embryo(s) you transfer during a fresh IVF cycle – or – a future Frozen Embryo Transfer (FET) procedure. NGS technology allows you the ability to balance the gender of your children as you plan your family. This is known as Family Balancing. The accuracy of gender selection through NGS is greater than 99 percent.

EmbryoScope Technology

The rare opportunity for patients to benefit from EmbryoScope technology at New Hope Fertility Center provides time-lapsed information and monitoring of every embryo’s development without disruption of in vitro culturing.

NGS Technology in Conjunction with IVF

Dr. John Zhang offers the highest success rates and best overall patient satisfaction through NGS technology in conjunction with IVF. To schedule your initial consultation with Dr. Zhang – call 917.525.5496.

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