Monthly Archives: November 2019

Natural Cycle IVF™ Can Help You Have a Baby

40724533 - beautiful pregnant woman doing sport in summer park.Our holistic Natural Cycle IVF™ is a personalized IVF treatment plan that does not require a woman to undergo a harsh regimen of fertility medication administration. By treating each of our patients as individuals, we are able to create IVF treatment plans customized for their specific needs. We encourage a woman’s body to produce her monthly one good egg.

Natural Cycle IVF™

The success of our holistic Natural Cycle IVF™ also improves a woman’s reproductive health. This is because we are steadfast in promoting our One Good Egg Policy. Our mission is to provide women with new and innovative fertility treatment protocols.

Every woman is different based on her unique medical history and fertility assessment. It is quality eggs that matter – not quantity.

We don’t refuse patients because a woman has been diagnosed as a difficult case.

  • No refusals based on a woman’s advanced maternal age
  • No refusals based on low FSH levels
  • No refusals based on the number of potential eggs (follicles) a woman can produce per fresh cycle
  • No refusals because a woman does not respond well to fertility medication

How Our Natural Cycle IVF™ Works

A woman’s body may need only a little coaxing to achieve a pregnancy with her one egg produced during a monthly menstrual cycle. A woman’s natural egg is the very best she can produce – without the need for numerous, costly, painful, self-administered fertility medication injections.

  • As a woman’s natural cycle begins, the doctor will monitor the growth of her one good egg through pelvic ultrasound imaging and blood tests
  • Once her natural egg has reached a prime stage of development, an ovulation trigger medication – hCG – will be self-administered by the patient at a designated time
  • On a scheduled date, her egg will be surgically retrieved in an outpatient procedure while the patient is under general anesthesia
  • After surgical retrieval, the egg will be fertilized in vitro through a procedure known as Intracytoplasmic Sperm Injection (ICSI)
  • ICSI is an ancillary IVF procedure in which one quality sperm is injected directly into the woman’s natural egg
  • The resulting embryo cultures in vitro to a high quality stage of development – up to 5 days
  • The high quality embryo is then transferred to the woman’s uterus via a thin catheter – similar to a Pap smear procedure
  • A pregnancy test is scheduled in approximately two weeks

Pregnancy Success Rates Using Natural Cycle IVF™

Even though fertility medications are not prescribed, the pregnancy success rates for our Natural Cycle IVF™ rivals those of Conventional IVF and Mini IVF™. The personal attention provided by our fertility support team provides every patient with the medication and technology needed to conceive.

  • No high cost, physically-challenging powerful fertility medications
  • A woman produces her one natural egg
  • Lowers health risks associated with Conventional IVF
  • Avoids the high cost associated with large dosages of fertility drugs
  • Helps women avoid the discomfort and side effects of daily fertility drug injections
  • Eliminates the potential of a multiple pregnancy
  • Resolves ethical and religious dilemmas for patients opposed to producing excess embryos

Candidates for Natural Cycle IVF™

Women who will most benefit from a Natural Cycle IVF™ protocol are those:

  • Women over 35 who have a regular menstrual period and are able to ovulate
  • Women over 35 with elevated FSH levels
  • Women over 35 with a poor ovarian reserve
  • Women diagnosed with Polycystic Ovarian Syndrome (PCOS)
  • Women who are at risk for Ovarian Hyperstimulation Syndrome (OHSS) due to high dosages of fertility medications
  • Women who want to avoid costly and painful fertility medication injections
  • Women who are unresponsive to fertility medications
  • Women who have been unable to produce multiple eggs during a Conventional IVF or Mini-IVF™ cycle
  • Women over 35 with elevated FSH levels and poor ovarian reserve
  • Women who do not want to produce multiple embryos for ethical or religious reasons

Natural Cycle IVF™ Expertise

It is important to work with a fertility doctor having the experience required to design a customized Natural Cycle IVF™ treatment protocol meeting your personal needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Centercall 917.525.5496.

You Can Adopt Frozen Embryos to Help You Have a Baby

Man With Baby (2)There is a growing trend for couples who have achieved pregnancy success through IVF to donate their excess frozen embryos in order to help others conceive. Look: One in six couples in America cannot conceive a biological child of their own. Frozen embryo adoption has successfully helped infertile couples build their families when other fertility treatments fail. Bottom Line: The success rate of IVF has led to an increase in the number of excess frozen embryos available to childless couples.

Adopt Frozen Embryos

Freezing excess, quality embryos after a fresh IVF cycle will increase a couple’s chances of conceiving in the future. This is not even the best part. Through embryo cryopreservation technology, couples can avoid the financial and physical strain of undergoing multiple fresh IVF cycles. That’s not all. Pregnancy success rates for a Frozen Embryo Transfers (FET) are higher than a fresh transfer because a woman has the opportunity to wait until her uterine lining returns to an ideal state for embryo implantation.

Frozen Embryo Transfer (FET)

Through FET, couples can repeatedly try to get pregnant using adopted frozen embryos. If the FET cycle is successful, couples can undergo another procedure at a Couples can plan their family through gender selection

  • Couples increase their chances for a healthy singleton pregnancy
  • Healthy pregnancies have been achieved after an embryo has been frozen for up to 10 years

Through world class laboratory technology, our pregnancy success rates through FET has increased substantially in recent years. That’s not all. Only high quality embryos are cryopreserve to be later transferred in future FET procedures. This success has made FETs an increasingly popular option to consider before considering a subsequent fresh IVF cycle. Bottom Line: With FET, couples can increase their chance of pregnancy per fresh egg retrieval and ultimately save money by avoiding the expense of another fresh IVF cycle.

FET Procedure

To begin the FET procedure, hormone medication is administered to suppress the woman’s pituitary gland and reduce the chances of unexpected ovulation. Estrogen acts to thicken and mature the uterine lining – like the natural estrogen produced by a developing egg follicle during a normal menstrual cycle.

During estrogen administration, monitoring of the uterine lining is required.

  • Transvaginal ultrasound for the doctor to evaluate the thickness of the uterine lining
  • Blood tests for the doctor to evaluate the level of estrogen in the blood

Double Benefit of FET: Monitoring for timing of transfer during a FET cycle is more flexible than in a fresh IVF cycle. The FET procedure is much less stressful on patients because the transfer date can be adjusted.

Progesterone is a medication administered in preparation for the FET to make the uterine lining receptive to the implantation of the embryo.

  • Progesterone matures the uterine lining
  • Progesterone creates a window of implantation in anticipation of a set FET date
  • Lupron injections are ceased upon the beginning of progesterone administration
  • Embryos are scheduled for thaw in the laboratory
  • FET is scheduled on a set date
  • Progesterone is continued daily to help prepare the patient’s uterine lining for implantation of the fertilized egg – the embryo
  • After the embryo transfer, a pregnancy test is scheduled on a date prescribed by the doctor through a blood draw

Healthy pregnancies have been achieved after an embryo has been frozen for up to 10 years. Pregnancy success through FETs is determined by the quality of the frozen embryo.

Single Embryo Transfers

Dr. John Zhang promotes the practice of Single Embryo Transfer (SET) to reduce health risks associated with multiple pregnancies and births. Cryopreservation of surplus embryos for future FET procedures is encouraged by the fertility specialists at New Hope Fertility Center in NYC – in lieu of repeated, expensive fresh IVF cycles.

-Pioneering Vitrification Method of Freezing Embryos

The flash-freezing technique of vitrification makes it possible to ready fresh embryos rapidly for cryopreservation. Using the vitrification method, embryos freeze quickly and damaging ice crystals do not form between cells. We are leaders in embryo cryopreservation. Dr. John Zhang was one of the first doctors in the United States to implement the vitrification method of embryo freezing.

Where to Adopt Frozen Embryos

To schedule your initial consultation with Dr. John Zhang about frozen embryo adoption at New Hope Fertility Centercall 917.525.5496.

Parents Magazine Recognizes Dr. Zhang’s Needle-Free IVF

Is the Future of IVF – Needle-Free? – Maressa Brown September 30, 2019

A fertility clinic in New York City has developed a form of in vitro fertilization that uses pills and a nasal spray, as well as urine and saliva tests instead of pricey injections and blood draws. Here’s what you need to know about needle-free IVF, or NF-IVF.

If you’re exploring IVF, you’ve learned about the bevy of side effects and steep cost of the conventional method. But what you might not have heard about just yet is a less invasive alternative called Needle-Free IVF, which is being touted as a groundbreaking technology offered exclusively by New Hope Fertility in New York City. Here’s what you need to know about the specifics and the cost of needle-free IVF.

The method was developed by John Zhang, MD, MSc, PhD, the founder/CEO of New Hope, in 2016. The unique method involves oral pills, vaginal suppositories, and nasal spray, but no injections, notes Zaher Merhi, MD, FACOG, the director of IVF research and development in IVF technologies at New York’s New Hope Fertility Center.

“Conventional IVF protocols have been used for over 35 years,” Dr. Merhi says. “It is about time to update IVF protocols to minimize risks and inconvenience related to conventional IVF. Conventional IVF involves daily injections and almost daily blood draws, which are too intense and heavy on patients’ body and mind. Injections are painful and expensive.”

To sidestep these uncomfortable aspects of traditional IVF, New Hope’s needle-free method involves oral and nasal fertility medications to more gently stimulate the ovaries into producing egg follicles. Because this process isn’t as rough on the body, patients are able to steer clear of conventional IVF side effects like weight gain—and get even higher-quality results, according to Dr. Merhi.

“If you think about pills and injections as food for the eggs, the less eggs there are, the less food they need,” Dr. Merhi explains. “Injections are strong food, so if you overfeed low number of eggs with injections, you will hurt their quality. A lot of studies have shown that less eggs retrieved due to minimal ovarian stimulation is correlated with better quality eggs.” This is especially true for women who are considered advanced maternal age (35+) and/or who have low ovarian reserve.

Like many conventional IVF patients, needle-free IVF patients start with a course of oral contraceptive tablets to prepare and stimulate the ovaries. But unlike conventional IVF, doctors will monitor the levels and baselines of pregnancy hormones (FSH, LH, estradiol, and progesterone) through urine and saliva, as opposed to daily blood draws. These tests “. . . are accurate for the hormone profiles that are needed for cycle monitoring, as long as the patient follows the instructions of the collection method,” Dr. Merhi says.

The patient then takes a “proprietary combination of nasal sprays” followed by a final spray for ovulation induction. Once a patient is cleared for retrieval, egg retrieval is done just as it would be with conventional IVF.

“Generally in the U.S., conventional IVF costs between $10,000-15,000,” Dr. Merhi says. By comparison, needle-free IVF will run between $5,000 and $7,000. The reason: “Conventional IVF involves taking injections which are very expensive,” according to Dr. Merhi.

Your chances of conception with needle-free IVF are “identical” to conventional IVF’s success rates, Dr. Merhi notes. That means that it varies from 40 to 65 percent in women under 35 and declines as women get older, down to less than 5 percent in women over 42.

Although needle-free IVF is suitable for any patient, it’s particularly useful for patients who:

  • Have a fear of needles
  • Want more natural and holistic fertility treatment options
  • Have Polycystic Ovarian Syndrome (PCOS)
  • Have problems self-administering medication
  • Experience discomfort or bruising due to injections
  • Avoid blood draws, perfect for women with difficult veins
  • Have a higher risk of OHSS (Ovarian Hyper-Stimulation Syndrome)

The only factor that would disqualify a patient from being a candidate for needle-free IVF is an allergy to the oral medications or vaginal suppositories. “Otherwise, everyone qualifies,” Dr. Merhi says. “So far, the majority of patients who have gone through NF-IVF love it.”

Needle-Free IVF Expertise

It is important to work with a Needle-Free IVF expert having the cutting-edge technology and clinical experience required to design a customized treatment plan meeting your financial and medical needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 917.525.5496.

How At-HOME IVF Treatment Can Help You Get Pregnant

Side table with books and flowers in bedroomYou can get pregnant At-HOME with the help of Dr. John Zhang’s innovative IVF treatment. This new IVF protocol is specifically designed to help you successfully conceive a baby at home.


This is an individually designed IVF pick-up or deliverable package containing everything you need for an At-HOME IVF cycle – including fertility medications.

Only one office visit is required for your outpatient egg retrieval.

  • Zero injections
  • Zero to minimal blood draws
  • Zero to minimal office monitoring visits
  • Lower treatment costs
  • No missed work
  • No pharmacy pick-ups
  • 24/7 personal assistance

At-HOME IVF is a patient-friendly protocol designed to eliminate the fear, pain, and anxiety experienced with injections and blood draws. The patient’s ovaries are stimulated into producing multiple egg follicles through the use of oral fertility medications.

Candidates for At-HOME IVF

  • Women with regular menstrual cycles – regardless of age
  • Women diagnosed with PCOS having irregular menstrual cycles

At-HOME IVF Benefits

Patients are treated in a less-invasive manner.

  • No shots
  • No needles
  • No injections
  • No blood draws
  • Only one office visit to perform your surgical egg retrieval

At-HOME Fertility Medications

Depending on the woman’s medical needs, an oral fertility medication – typically Clomid and/or Letrozole– are prescribed to gently stimulate her ovaries into producing multiple eggs. Synarel is administered nasally for 3 days at the beginning of the cycle and then again 36 hours prior to surgical egg retrieval to trigger ovulation.

  • Clomid and/or Femara to stimulate egg production
  • Synarel to trigger ovulation
  • Oral progesterone tablets
  • Vaginal progesterone suppositories

One Good Egg Policy

Customized IVF care is the best. Remember: It only takes one good egg and one healthy sperm to make a baby. Our focus is to help you produce good quality eggs during a fresh IVF cycle – not a high quantity of eggs using large doses of injectable fertility medications.  This policy is perfectly suited for our new Needle-Free IVF protocol.

Difficult Patients Welcome

Women diagnosed as difficult or hopelessly infertile by other fertility clinics are welcomed at New Hope Fertility Center. Because of our One Good Egg Policy, we happily accept candidates for IVF that other fertility clinics decline to treat and have proven success where others failed to even try.

High Tech IVF Laboratory

Our goal is to maximize every patient’s chances of having a successful pregnancy. At New Hope Fertility Center, we offer the latest:

  • IVF technology
  • IVF ingenuity
  • IVF customization

Our IVF laboratory is comprised of a powerful air filtration system to facilitate the best conditions for success of procedures and research. We have one of the largest and most powerful air filtration systems in the world. This quality air filtration system provides optimal clean air pressure in every laboratory process.

IVF Expertise

It is important to work with an IVF expert having the cutting-edge technology and clinical experience required to design a customized treatment plan meeting your financial and medical needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 917.525.5496.