A fertility clinic in New York City has developed a form of in vitro fertilization that uses pills and a nasal spray, as well as urine and saliva tests instead of pricey injections and blood draws. Here’s what you need to know about needle-free IVF, or NF-IVF.
If you’re exploring IVF, you’ve learned about the bevy of side effects and steep cost of the conventional method. But what you might not have heard about just yet is a less invasive alternative called Needle-Free IVF, which is being touted as a groundbreaking technology offered exclusively by New Hope Fertility in New York City. Here’s what you need to know about the specifics and the cost of needle-free IVF.
The method was developed by John Zhang, MD, MSc, PhD, the founder/CEO of New Hope, in 2016. The unique method involves oral pills, vaginal suppositories, and nasal spray, but no injections, notes Zaher Merhi, MD, FACOG, the director of IVF research and development in IVF technologies at New York’s New Hope Fertility Center.
“Conventional IVF protocols have been used for over 35 years,” Dr. Merhi says. “It is about time to update IVF protocols to minimize risks and inconvenience related to conventional IVF. Conventional IVF involves daily injections and almost daily blood draws, which are too intense and heavy on patients’ body and mind. Injections are painful and expensive.”
To sidestep these uncomfortable aspects of traditional IVF, New Hope’s needle-free method involves oral and nasal fertility medications to more gently stimulate the ovaries into producing egg follicles. Because this process isn’t as rough on the body, patients are able to steer clear of conventional IVF side effects like weight gain—and get even higher-quality results, according to Dr. Merhi.
“If you think about pills and injections as food for the eggs, the less eggs there are, the less food they need,” Dr. Merhi explains. “Injections are strong food, so if you overfeed low number of eggs with injections, you will hurt their quality. A lot of studies have shown that less eggs retrieved due to minimal ovarian stimulation is correlated with better quality eggs.” This is especially true for women who are considered advanced maternal age (35+) and/or who have low ovarian reserve.
Like many conventional IVF patients, needle-free IVF patients start with a course of oral contraceptive tablets to prepare and stimulate the ovaries. But unlike conventional IVF, doctors will monitor the levels and baselines of pregnancy hormones (FSH, LH, estradiol, and progesterone) through urine and saliva, as opposed to daily blood draws. These tests “. . . are accurate for the hormone profiles that are needed for cycle monitoring, as long as the patient follows the instructions of the collection method,” Dr. Merhi says.
The patient then takes a “proprietary combination of nasal sprays” followed by a final spray for ovulation induction. Once a patient is cleared for retrieval, egg retrieval is done just as it would be with conventional IVF.
“Generally in the U.S., conventional IVF costs between $10,000-15,000,” Dr. Merhi says. By comparison, needle-free IVF will run between $5,000 and $7,000. The reason: “Conventional IVF involves taking injections which are very expensive,” according to Dr. Merhi.
Your chances of conception with needle-free IVF are “identical” to conventional IVF’s success rates, Dr. Merhi notes. That means that it varies from 40 to 65 percent in women under 35 and declines as women get older, down to less than 5 percent in women over 42.
Although needle-free IVF is suitable for any patient, it’s particularly useful for patients who:
The only factor that would disqualify a patient from being a candidate for needle-free IVF is an allergy to the oral medications or vaginal suppositories. “Otherwise, everyone qualifies,” Dr. Merhi says. “So far, the majority of patients who have gone through NF-IVF love it.”
It is important to work with a Needle-Free IVF expert having the cutting-edge technology and clinical experience required to design a customized treatment plan meeting your financial and medical needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.
When you undergo a cutting-edge Mini-IVF™ protocol – you will produce 3 to 5 high quality eggs in one treatment cycle. Look: When only quality eggs are produced, your chance of a successful pregnancy is dramatically increased. Plus, you will spend less on fertility medications because you will be prescribed lower dosages. The best part: Your body won’t be overtaxed by having to produce the 10 to 15 eggs typically reached in a Conventional IVF Cycle – which may or may not be of good quality.
First Class IVF Technology, ingenuity, and standards set New Hope Fertility Center apart from all other fertility clinics – worldwide. Look: Our patients are our first priority and we strive to provide stellar IVF treatment through a customized, evidence-based approach. Bottom Line: We have designed a cutting-edge environment with the specific goal of maximizing every patient’s chances of having a baby.
Through our new IVF technology, ingenuity, and high standards of care, every patient receives superior IVF treatment.
That’s not the best part. Our IVF laboratory is designed with a powerful air filtration system supporting the success of our intricate procedures and research. Why is this important? This controlled air system facilitates an uncontaminated environment.
New Hope Fertility Center boasts one of the largest and most powerful laboratory air filtration systems in the world. Having both cooling and purification air filtration systems, our lab facility provides optimal clean air pressure for the performance of intricate IVF technology.
Yearly ART data on IVF success rates is a rich source of information for potential IVF patients. This data gives patients an idea of their average chances of pregnancy success through IVF. At New Hope Fertility Center, IVF success rates vary in the context of patient and treatment characteristics:
Only a cutting-edge Mini- IVF clinic will receive IVF success stories from their patients. At New Hope Fertility Center, we strive to maintain our position as a cutting-edge IVF clinic by producing high pregnancy success rates. Our reputation as a first class IVF clinic, has earned us the status of being a renowned leader in IVF globally.
At New Hope Fertility Center, we welcome difficult patients – those previously diagnosed by other fertility specialists as hopelessly infertile.
It is important to work with a Mini-IVF ™ fertility doctor having cutting-edge technology. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.
IVF pregnancy success rates using a Frozen Embryo Transfer (FET) are higher than a fresh embryo transfer. Look: The patient’s body has the opportunity to wait until her uterine lining returns to an ideal state for embryo implantation. Freezing quality embryos after a fresh IVF cycle will increase a couple’s chance of conceiving in the future. This is not even the best part. Through embryo cryopreservation technology, couples can avoid the financial and physical strain of undergoing multiple fresh IVF cycles.
Through FET, couples can try again – sooner than later – if their fresh IVF cycle fails. If the fresh IVF cycle is successful, the couple can undergo a FET at a time when they decide to have more children in the future.
Through world class laboratory technology, our pregnancy success rates through FET has increased substantially in recent years. That’s not all. Only high quality embryos are cryopreserve to be later transferred in future FET procedures. This success has made FETs an increasingly popular option to consider before considering a subsequent fresh IVF cycle. Bottom Line: With FET, couples can increase their chance of pregnancy per fresh egg retrieval and ultimately save money by avoiding the expense of another fresh IVF cycle.
To begin the FET procedure, hormone medication is administered to suppress the woman’s pituitary gland and reduce the chances of unexpected ovulation. Estrogen acts to thicken and mature the uterine lining – like the natural estrogen produced by a developing egg follicle during a normal menstrual cycle.
During estrogen administration, monitoring of the uterine lining is required.
Double Benefit of FET: Monitoring for timing of transfer during a FET cycle is more flexible than in a fresh IVF cycle. The FET procedure is much less stressful on patients because the transfer date can be adjusted.
Progesterone is a medication administered in preparation for the FET to make the uterine lining receptive to the implantation of the embryo.
Healthy pregnancies have been achieved after an embryo has been frozen for up to 10 years. Pregnancy success through FETs is determined by the quality of the frozen embryo.
Our fertility specialists promote the practice of Single Embryo Transfer (SET) to reduce health risks associated with multiple pregnancies and births. Cryopreservation of surplus embryos for future FET procedures is encouraged by the fertility specialists at New Hope Fertility NYC – in lieu of repeated, expensive fresh IVF cycles.
The flash-freezing technique of vitrification makes it possible to ready fresh embryos rapidly for cryopreservation. Using the vitrification method, embryos freeze quickly and damaging ice crystals do not form between cells. We are leaders in embryo cryopreservation. Dr. John Zhang was one of the first doctors in the United States to implement the vitrification method of embryo freezing.
It is important to work with a frozen embryo transfer expert having the clinical experience required to design a customized IVF treatment plan meeting your personal needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.
Next Thursday @ 6:30 p.m. – December 12th – you are invited to join our FREE egg freezing social hosted by Dr. Meir Olcha at 4 Columbus Circle – 3rd Floor – in NYC. You will discover everything you need to know about egg freezing. This social event is designed to present our cutting-edge egg freezing in conjunction with IVF. Why do we offer free egg freezing social events? Because every woman needs more information and realistic data about preserving her future ability to have biologically-related children.
Our December 12th egg freezing social event will cover:
Success rates for egg freezing have improved significantly in recent years. Women should be informed of their opportunity to freeze their eggs for social reason if they chose not to get pregnant within their prime reproductive years. These women should be aware that egg freezing does not guaranty a baby in the future. – The Guardian
The latest data from the Human Fertilisation and Embryo Authority (HFEA) shows the following trends in egg freezing:
Social egg freezing should be offered to single women approaching their mid-thirties. Improvements in egg freezing technologies mean a greater chance of egg-thawing survival today. Women should not be faced with childlessness because they cannot find the right partner – nor should they feel pressured into a relationship because of an aging ovarian reserve. – The Guardian
When you sign up for an egg freezing consultation, you will receive:
Your eggs don’t have to age – even if you do!
Egg Freezing is affordable at New Hope Fertility Center.
Because every patient’s personal, medical, and financial needs are different, we offer customized IVF treatment.
Pregnancy success rates using a woman’s egg that has been cryopreserved are comparable to success rates using a fresh egg.
Successfully increasing IVF Pregnancy Success Rates requires all-encompassing fertility care. At New Hope Fertility Center, we have comprised a team of World Class Fertility Specialists who are committed to working in tandem to bring every patient tomorrow’s cutting edge IVF treatment – today.
It is important to work with a fertility doctor having the research and clinical experience required to design a customized egg freezing plan meeting your personal and medical needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.
Non-Invasive Chromosomal Screening (NICS) is an innovative and non-invasive genetic testing method used to detect chromosomal abnormalities in embryos culturing in vitro. NICS increases IVF and FET pregnancy success rates by up to 30%. NICS is an in vitro evaluation of the efficacy of a single-embryo transfer at the blastocyst stage (5 days growth). NICS is the sequencing of free genomic DNA in the culture medium of individual blastocysts and obtaining chromosomal ploidy information.
The development of NICS technology at New Hope Fertility Center marks a huge and truly a momentous achievement. We are now one of only a handful of centers around the world offering a validated and accurate platform for analyzing embryologic DNA in a completely non-invasive fashion.
This cutting-edge technology detects chromosomal deficiencies in embryos – aneuploidy – an extra or missing chromosome.
When abnormal embryos detected using NICS, they are discarded. Only quality embryos are transferred to the mother’s uterus – or – frozen (cryopreserved) for future FETs.
Other benefits of NICS in conjunction with IVF include:
NICS Can Increase IVF Pregnancy Success Rate Up To 30 Percent!
State-of-the-art genetics technologies have proven to increase IVF pregnancy rates. Through the medical marvel of NICS in conjunction with IVF, genetic and chromosomal abnormalities can be detected in embryos.
As a woman advances in age, the chance for low quality embryos increases.
Low quality embryos result in:
Dr. John Zhang’s NICS technology expertise in conjunction with IVF offers the highest pregnancy success rates and best overall patient satisfaction. To schedule your initial consultation, call 212.969.7422.
Dr. John Zhang is proud to offer a new IVF protocol specifically designed to help you successfully conceive a baby at home. You can now conveniently get pregnant with At-HOME IVF. Only one office visit is required for your outpatient egg retrieval. This is an individually designed IVF pick-up or deliverable package containing everything you need for an At-HOME IVF cycle – including fertility medications.
At-HOME IVF is a patient-friendly protocol designed to eliminate the fear, pain, and anxiety experienced with injections and blood draws. The patient’s ovaries are stimulated into producing multiple egg follicles through the use of oral fertility medications.
Patients are treated in a less-invasive manner.
Depending on the woman’s medical needs, an oral fertility medication – typically Clomid and/or Letrozole – is prescribed to gently stimulate her ovaries into producing multiple eggs. Synarel is administered nasally for 3 days at the beginning of the cycle and then again 36 hours prior to surgical egg retrieval to trigger ovulation.
Customized IVF care is the best. Remember: It only takes one good egg and one healthy sperm to make a baby. Our focus is to help you produce good quality eggs during a fresh IVF cycle – not a high quantity of eggs using large doses of injectable fertility medications. This policy is perfectly suited for our new Needle-Free IVF protocol.
Our goal is to maximize every patient’s chances of having a successful pregnancy. At New Hope Fertility Center, we offer the latest:
Our IVF laboratory is comprised of a powerful air filtration system to facilitate the best conditions for success of procedures and research. We have one of the largest and most powerful air filtration systems in the world. This quality air filtration system provides optimal clean air pressure in every laboratory process.
It is important to work with an IVF expert having the cutting-edge technology and clinical experience required to design a customized treatment plan meeting your financial and medical needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.
A positive IVF attitude is crucial to making make sure you have the best chance of conceiving a successful pregnancy. Being proactive with your mental and emotional health care is key. A woman’s whole body health benefits from fertility counseling during IVF treatment. Many challenges can be addressed through individual, couple, and group counseling.
Professional In-House Fertility Counseling with Allison Rosen Ph.D. is recommended by the fertility specialists at New Hope Fertility Center. That’s not all: We are dedicated to promoting how patients can increase their chances of achieving a healthy pregnancy through genetic testing in conjunction with In Vitro Fertilization (IVF).
As an experience clinical psychologist specializing in infertility, Dr. Allison Rosen has helped hundreds of couples cope during their struggle to have a baby.
Through individual, couple, and group counseling, the Doctor addresses the many challenges of dealing with infertility including:
Today’s Assisted Reproductive Technology (ART) helps to increase the healthy birth rates of babies through genetic testing. This is because only the healthiest embryos are transferred for implantation during a fresh IVF cycle and/or Frozen Embryo Transfer (FET). Genetic testing helps to reduce the number of cycles required to achieve a healthy pregnancy.
PGS is the testing of an embryo’s overall chromosomal normalcy prior to being transferred to the patient’s uterus in conjunction with IVF. PGS detects chromosomal deficiencies – aneuploidy – an extra or missing chromosome in an embryo.
PGS Increases Pregnancy Success Rates Up To 30%
PGS dramatically increases a woman’s chance of conception. Only the healthiest embryo(s) are transferred. Embryo biopsy and screening can increase a patient’s chance of a successful pregnancy by up to 30 percent.
Because advanced maternal age (over 35) adversely affects the quality of a woman’s eggs – oocytes – resulting in chromosomal abnormalities, New Hope Fertility NYC recommends PGS in conjunction with IVF to patients over the age of 35.
By extracting a cell from an embryo and analyzing it, poor quality embryos are detected. Biopsy of this cell will not damage the embryo.
Low quality embryos result in:
NGS is a new method of PGS. NGS is the latest genetic screening test for primary candidates undergoing IVF. NGS is used for comprehensive chromosome testing of embryos created through IVF. NGS is on the horizon to replacing PGS because of the procedure’s lower cost and reduced errors.
NGS allows embryologists to screen for defects on the chromosomal level with higher accuracy and more detail than ever before. PGS results are comprehensive and a higher resolution than any other genetic testing method because it detects more translocations.
NGS is also helpful for those couples wanting to plan their family through gender selection.
It is important to work with a fertility counselor when you undergo fertility treatment. To schedule your initial consultation with Dr. Allison Rosen at New Hope Fertility Center call 212.969.7422.
A streamlined fertility team approach provides evidence-based higher IVF pregnancy success rates. It is not necessary for you to consult with your fertility doctor at every blood draw and ultrasound monitoring visit. A streamlined approach is cost-efficient IVF. Our team works in tandem with your fertility doctor at every stage of treatment.
A streamlined fertility team approach to IVF treatment is the most successful at increasing pregnancy success rates.
The multidisciplinary team at New Hope Fertility Center is comprised of world renowned fertility doctors, plus ultra-talented:
Our multidisciplinary team has substantial experience in the practice of Assisted Reproductive Technology (ART) and OBGYN.
Members of the fertility team at New Hope Fertility Center are professionals who have earned:
Through a streamline approach, your primary doctor is always fully informed about your progress by the multidisciplinary fertility team.
At New Hope Fertility Center, all patient cases are evaluated, reviewed and discussed by and between their multidisciplinary fertility team. The team collectively arrives at and executes the best customized fertility treatment plan based upon every patient’s individualized needs.
To increase your chances of pregnancy, place your trust in a multidisciplinary fertility team approach. Contact the Fertility Experts at New Hope Fertility Center if you’re struggling with infertility. It is important to work with a fertility care team having a thorough understanding of the root cause of your infertility.
A multidisciplinary team approach to treating your infertility will:
It is important to work with a fertility doctor having the expertise required to design a customized IVF treatment protocol meeting your personal needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.
Gender selection is socially acceptable and gaining in popularity. No longer is gender selection stigmatized as a social engineering tool used to make designer babies. Gender identification and selection technology can easily help you choose the sex of your baby. PGS/NGS technology in conjunction with IVF will help you choose the sex of your baby with 99% accuracy. You can balance the sexes of your future family with genetic testing technology.
Gender selection is a beneficial by-product of genetic testing. The good news: Through genetic testing, the sex of each embryo is identifiable. PGS and NGS technology works to identify embryos with chromosomal abnormalities while they culture in vitro (in the lab). Why is this important? PGS/NGS is the testing of an embryo’s overall chromosomal normalcy prior to being transferred to the patient’s uterus. Chromosomal abnormalities make an embryo too week to thrive into a fetus if it manages to implant into a woman’s uterine lining.
The chromosomes of a sperm determine an embryo’s gender.
We recommend universal blastocyst embryo screening for our patients because the procedure can help increase the chances of a pregnancy by 30 percent. Our fertility specialists recommend PGS/NGS in conjunction with IVF for:
State-of-the-art embryo biopsy techniques and genetics technologies have proven to increase IVF pregnancy rates. Through the medical marvel of PGS/NGS in conjunction with IVF, genetic and chromosomal abnormalities can be detected in embryos.
As a woman advances in age, the chance for chromosomal abnormalities in embryos increases. Low quality embryos result in:
PGS/NGS takes place in conjunction with IVF in a controlled laboratory setting. Three days after fertilization of the patient’s eggs in vitro, cells are removed from each of the embryos developing.
The benefits of PGS/NGS in conjunction with IVF include:
Our Mini-IVF™ can increase your chances of pregnancy without the need for large dosages of costly fertility medications used to produce an excessive number of eggs. Here’s the deal: The goal with a Mini-IVF™ protocol is to produce between 3 and 5 quality eggs per fresh cycle. The best part: Pregnancy success rates for Mini-IVF™ are comparable to Conventional IVF.
To schedule your gender selection consultation with Dr. John Zhang call 212.969.7422.
The Doctor practices with compassion and trust every day. Every person has the right to have a family of their own. This has been our mission statement since 2004 – the year New Hope Fertility Center was founded in NYC by Dr. Zhang. Sexual orientation bias has no place in the practice of fertility. The Doctor is renowned worldwide for providing cutting-edge LGBTQ fertility treatment to our same-sex patients. Dr. Zhang steadfastly pursues his mission of reducing the physical, emotional, and financial toll of every LGBTQ patient during their quest to have a baby.
Gestational Surrogacy – selecting and using donor eggs fertilized in vitro with the sperm from one of the partners
Gestational surrogacy can be used to achieve a pregnancy through IVF using:
Egg Donor Recipients – selecting and using donor eggs to accomplish gestational surrogacy
Fertility Treatment Options for Female Couples
You can realize your dream of building a family by using cutting-edge reproductive technologies.
Regardless of the gender combination of LGBTQ couples – or singles wanting to be a solo parent – the process of selecting donor eggs or donor sperm has been substantially streamlined for our patients’ ease.
World class – yet affordable – support packages for the selection of donor eggs and donor sperm are offered. Our donor program is extremely successful because we use the most cutting-edge cryopreservation and IVF technologies.
The most common fertility treatment for lesbian couples is IUI. Timed with induced ovulation, the patient is artificially inseminated with a highly concentrated amount of motile donor sperm. The IUI procedure is performed in the doctor’s office and requires no anesthesia.
Two IUI inseminations are performed between 12 and 36 hours after hCG administration to increase the patient’s chances of pregnancy.
One partner’s eggs are harvested for IVF using donor sperm. The other partner carries the pregnancy.
Gestational Surrogacy – Using donor eggs to be fertilized with the sperm from one of the partners. The resulting embryo is transferred to a surrogate who will carry the baby.
Egg Donor Recipient Program – Acquiring donor eggs to accomplish gestational surrogacy.
Gestational surrogacy may be used to achieve a pregnancy and birth using a surrogate mother.
It is important to work with a fertility doctor having the research and clinical experience required to design a customized LGBTQ treatment plan meeting your personal and medical needs. To schedule your initial consultation with Dr. John Zhang at New Hope Fertility Center – call 212.969.7422.